Is the surname you folks posting about Griffin or Griffith or are they the same?
Crystal, found this and it sounds like this line might be connected with Fort Christanna:
http://www.geocities.com/frankoclark/richland/griffin.html
John Griffin’s family received a 250 acres grant on the waters of the Congaree (Toms and Griffins Creek area) in the year 1764. These Griffins were part of the large “free-person-of-color” community in Richland County c1790-1850. Were these the “Sandhillers?” John was possibly half Indian, perhaps Cherokee. His wife’s father was part Saponi from North Carolina. Absalom GRIFFIN, who lived in Richland c1770, was not listed as a person of color, so he and John may have been a half brothers. Sons were Gideon, Morgan and John. Daughter was Hannah or Johannah.
First Generation:
John2 Griffin (son of Joseph1 and Joyce) was born 08 Oct 1719 in Colonial SC, probably in St. Georges Parish near Charleston. He died 1771 in St. Marks Parish SC, in what later would be Richland County. His first wife was probably (1) (Indian) married about 1740. He later married (2) Agnes about 1747. He married his last wife (3) Mary much later.